产品货号：
Z21674
中文名称：
NALP4/NLRP4抗体
英文名称：
Anti-NALP4/NLRP4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NALP4/NLRP4 Antibody |
| 指标别名 | CT58;PAN2;RNH2;NALP4;PYPAF4;CLR19.5;NACHT;LRR and PYD domains-containing protein 4;PAAD and NACHT-containing protein 2;CT58 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | NLRP4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NALP4 antibody was raised against a 13 amino acid synthetic peptide near the center of human NALP4.The immunogen is located within amino acids 330 - 380 of NALP4. |
| 计算分子量 | 113kDa |
| 成分 | NALP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NALP4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction.NALP4,also known as PYRIN-containing APAF1-like protein 4,has a C-terminal leucine-rich repeat (LRR) region,an N-terminal Pyrin domain (PYD) followed by a NACHT domain,and a NACHT-associated domain.In transfected 293 cells,NALP4 suppressed NF-百B induction by TNF-汐and IL-1汕，suggesting NALP4 operates at a point of convergence in these two signaling pathways.NALP4 also suppressed NF-百B induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways,including TRAF2,TRAF6,RIP,and IRAK2,as well as the IKK-alpha and IKK-beta,suggesting that NALP4 is critical in modulating NF-百B activity. |
| Uniprot ID | Q96MN2 |
| 基因名全称 | NLR family,pyrin domain containing 4 |
| 蛋白名全称 | NLR family,pyrin domain containing 4 |
| 推荐稀释比 | NALP4 antibody can be used for detection of NALP4 by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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